Pairwise and Multi-chain Protein Docking Enhanced Using LZerD Web Server.

ABSTRACT: Interactions of proteins with other macromolecules have important structural and functional roles in the basic processes of living cells. To understand and elucidate the mechanisms of interactions, it is important to know the 3D structures of the complexes. Proteomes contain numerous protein-protein complexes, for which experimentally determined structures often do not exist. Computational techniques can be a practical alternative to obtain useful complex structure models. Here, we present a web server that provides access to the LZerD and Multi-LZerD protein docking tools, which can perform both pairwise and multi-chain docking. The web server is user-friendly, with options to visualize the distribution and structures of binding poses of top-scoring models. The LZerD web server is availab

SUBMITTER: Harini K 

PROVIDER: S-EPMC10561630 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature