The Structural Layers of the Porcine Iris Exhibit Inherently Different Biomechanical Properties.

ABSTRACT:

Purpose

The purpose of this study was to isolate the structural components of the ex vivo porcine iris tissue and to determine their biomechanical properties.

Methods

The porcine stroma and dilator tissues were separated, and their dimensions were assessed using optical coherence tomography (OCT). The stroma underwent flow test (n = 32) to evaluate for permeability using Darcy's Law (ΔP = 2000 Pa, A = 0.0391 mm2), and both tissues underwent stress relaxation experiments (ε = 0.5 with initial ramp of δε = 0.1) to evaluate for their viscoelastic behaviours (n = 28). Viscoelasticity was characterized by the parameters β (half width of the Gaussian distribution), τm (mean relaxation time constant), E0 (instantaneous modulus), and E∞ (equilibrium modulus).

Results

For the

SUBMITTER: Tan RKY 

PROVIDER: S-EPMC10561784 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature