Ontology highlight
ABSTRACT:
SUBMITTER: Jelen M
PROVIDER: S-EPMC10561975 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Jelen Meghan M Musso Pierre-Yves PY Junca Pierre P Gordon Michael D MD
eLife 20230926
Tastes typically evoke innate behavioral responses that can be broadly categorized as acceptance or rejection. However, research in <i>Drosophila melanogaster</i> indicates that taste responses also exhibit plasticity through experience-dependent changes in mushroom body circuits. In this study, we develop a novel taste learning paradigm using closed-loop optogenetics. We find that appetitive and aversive taste memories can be formed by pairing gustatory stimuli with optogenetic activation of se ...[more]