Recovery of right ventricular function after intermediate-risk pulmonary embolism: results from the multicentre Pulmonary Embolism International Trial (PEITHO)-2.

ABSTRACT:

Background

Right ventricular (RV) function plays a critical role in the pathophysiology and acute prognosis of pulmonary embolism (PE). We analyzed the temporal changes of RV function in the cohort of a prospective multicentre study investigating if an early switch to oral anticoagulation in patients with intermediate-risk PE is effective and safe.

Methods

Echocardiographic and laboratory examinations were performed at baseline (PE diagnosis), 6 days and 6 months. Echocardiographic parameters were classified into categories representing RV size, RV free wall/tricuspid annulus motion, RV pressure overload and right atrial (RA)/central venous pressure.

Results

RV dysfunction based on any abnormal echocardiographic parameter was present in 84% of patients at baseline. RV

SUBMITTER: Mavromanoli AC 

PROVIDER: S-EPMC10562278 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature