The two-component system CpxAR is required for the high potassium stress survival of Actinobacillus pleuropneumoniae.

ABSTRACT:

Introduction

Actinobacillus pleuropneumoniae is an important respiratory pathogen, which can cause porcine contagious pleuropneumonia and lead to great economic losses to worldwide swine industry. High potassium is an adverse environment for bacteria, which is not conducive to providing turgor pressure for cell growth and division. Two-component system CpxAR is an important regulatory system of bacteria in response to environmental changes, which is involved in a variety of biological activities, such as antibiotic resistance, periplasmic protein folding, peptidoglycan metabolism and so on.

Methods

However, little is known about the role of CpxAR in high potassium stress in A. pleuropneumoniae. Here, we showed that CpxAR is critical for cell division of A. pleuropn

SUBMITTER: Wan J 

PROVIDER: S-EPMC10562621 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature