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Hyperbaric oxygen therapy as a complementary treatment in neuroblastoma - a narrative review.


ABSTRACT: Neuroblastoma is the most frequently diagnosed cancer during the first year of life. This neoplasm originates from neural crest cells derived from the sympathetic nervous system, adrenal medulla, or paraspinal ganglia. The clinical presentation can vary from an asymptomatic mass to symptoms resulting from local invasion and/or spread of distant disease spread. The natural history of neuroblastoma is highly variable, ranging from relatively indolent biological behavior to a high-risk clinical phenotype with a dismal prognosis. Age, stage, and biological features are important prognostic risk stratification and treatment assignment prognostic factors. The multimodal therapy approach includes myeloablative chemotherapy, radiotherapy, immunotherapy, and aggressive surgical resection. Hyperbari

SUBMITTER: Alpuim Costa D 

PROVIDER: S-EPMC10562625 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature