Optimal positive end-expiratory pressure titration of intraoperative mechanical ventilation in different operative positions of female patients under general anesthesia.

ABSTRACT:

Objective

This study aimed to compare the effectiveness and safety of different titrated methods used to determine individual positive end-expiratory pressure (PEEP) for intraoperative mechanical ventilation in female patients undergoing general anesthesia in different operative positions, and provide reference ranges of optimal PEEP values based on the titration.

Methods

A total of 123 female patients who underwent elective open abdominal surgery under general anesthesia were included in this study. After endotracheal intubation, patients' body position was adjusted to the supine position, Trendelenburg positions at 10° and 20° respectively. PEEP was titrated from 20 cmH₂O to 4 cmH₂O, decreasing by 2 cmH₂O every 1 min. Electrical impedance t

SUBMITTER: Shu B 

PROVIDER: S-EPMC10562915 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature