Ontology highlight
ABSTRACT: Objective
To provide guidance for the management of gout, including indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations.Methods
Fifty-seven population, intervention, comparator, and outcomes questions were developed, followed by a systematic literature review, including network meta-analyses with ratings of the available evidence according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology, and patient input. A group consensus process was used to compose the final recommendations and grade their strength as strong or conditional.Results
Forty-two recommendations (including 16 strong recommendations) were generated. Strong recommendation
SUBMITTER: FitzGerald JD
PROVIDER: S-EPMC10563586 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature