Left bundle branch pacing with and without anodal capture: impact on ventricular activation pattern and acute haemodynamics.

ABSTRACT:

Aims

Left bundle branch pacing (LBBP) can deliver physiological left ventricular activation, but typically at the cost of delayed right ventricular (RV) activation. Right ventricular activation can be advanced through anodal capture, but there is uncertainty regarding the mechanism by which this is achieved, and it is not known whether this produces haemodynamic benefit.

Methods and results

We recruited patients with LBBP leads in whom anodal capture eliminated the terminal R-wave in lead V1. Ventricular activation pattern, timing, and high-precision acute haemodynamic response were studied during LBBP with and without anodal capture. We recruited 21 patients with a mean age of 67 years, of whom 14 were males. We measured electrocardiogram timings and haemodynamics in all pa

SUBMITTER: Ali N 

PROVIDER: S-EPMC10563660 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature