A transcriptional and regulatory map of mouse somite maturation.
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ABSTRACT:
SUBMITTER: Ibarra-Soria X
PROVIDER: S-EPMC10563765 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Publications
A transcriptional and regulatory map of mouse somite maturation.
Ibarra-Soria Ximena X Thierion Elodie E Mok Gi Fay GF Münsterberg Andrea E AE Odom Duncan T DT Marioni John C JC
Developmental cell 20230726 19
The mammalian body plan is shaped by rhythmic segmentation of mesoderm into somites, which are transient embryonic structures that form down each side of the neural tube. We have analyzed the genome-wide transcriptional and chromatin dynamics occurring within nascent somites, from early inception of somitogenesis to the latest stages of body plan establishment. We created matched gene expression and open chromatin maps for the three leading pairs of somites at six time points during mouse embryo ...[more]
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