ESOMIR: a curated database of biomarker genes and miRNAs associated with esophageal cancer.

ABSTRACT: 'Esophageal cancer' (EC) is a highly aggressive and deadly complex disease. It comprises two types, esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC), with Barrett's esophagus (BE) being the only known precursor. Recent research has revealed that microRNAs (miRNAs) play a crucial role in the development, prognosis and treatment of EC and are involved in various human diseases. Biological databases have become essential for cancer research as they provide information on genes, proteins, pathways and their interactions. These databases collect, store and manage large amounts of molecular data, which can be used to identify patterns, predict outcomes and generate hypotheses. However, no comprehensive database exists for EC and miRNA relationships. To address this g

SUBMITTER: Sindhoo A 

PROVIDER: S-EPMC10563827 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature