A Prussian blue analog as a decorporation agent for the simultaneous removal of cesium and reactive oxygen species.

ABSTRACT: Radioactive cesium (Cs) is a significant concern due to its role as a major byproduct of nuclear fission and its potential for radioactive contamination. Internal contamination with radioactive Cs is characterized by immoderate production of reactive oxygen species (ROS), resulting in severe radiation damage. Therefore, the development of therapeutic strategies should focus on enhancing the excretion of radioactive Cs and reducing radiation-induced oxidative damage. However, current therapeutic drugs like Prussian blue (PB) have limited efficacy in addressing these issues. In this study, we present Cu₃[Fe(CN)₆]₂ (CuFe) nanoparticles, a Prussian blue analog (PBA), which can not only efficiently sequester Cs but also exhibit resistance against radiation damag

SUBMITTER: Xue T 

PROVIDER: S-EPMC10563846 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature