Comparison of Noninvasive Mechanical Ventilation With High-Flow Nasal Cannula, Face-Mask, and Helmet in Hypoxemic Respiratory Failure in Patients With COVID-19: A Randomized Controlled Trial.

ABSTRACT:

Objectives

For COVID-19-related respiratory failure, noninvasive respiratory assistance via a high-flow nasal cannula (HFNC), helmet, and face-mask noninvasive ventilation is used. However, which of these options is most effective is yet to be determined. This study aimed to compare the three techniques of noninvasive respiratory support and to determine the superior technique.

Design

A randomized control trial with permuted block randomization of nine cases per block for each parallel, open-labeled arm.

Setting and patients

Adult patients with COVID-19 with a Pa o2 /F io2 ratio of less than 300, admitted between February 4, 2021, and August 9, 2021, to three tertiary centers in Oman, were studied.

Interventions

This study included three interventions: HFNC ( n

SUBMITTER: Al Hashim AH 

PROVIDER: S-EPMC10563904 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature