Identifying optimal ranges of weight gain at the end of the second trimester result from a population-based cohort study.

ABSTRACT:

Objective

To identify the optimal weight gain at the end of the second trimester.

Design

This was a population-based cohort study from the antenatal care system in Tianjin, China. We calculated gestational weight gain (GWG) based on the weight measured in the first trimester and the end of the second trimester. Restricted cubic spline analysis was performed to model the possible non-linear relationships between GWG and adverse outcomes. The optimal GWG was defined as the value of the lowest risk. Non-inferiority margins and the shape of the spline curves identified the recommended ranges in Chinese-specific BMI categories.

Setting

Tianjin Maternal and Child Health Cohort.

Participants

Singleton pregnant women aged 18-45 years.

Results

In total, 69 859 pr

SUBMITTER: Zhang S 

PROVIDER: S-EPMC10564611 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature