Prognostic effect of HIV on visual acuity in ocular syphilis: a systematic review.

ABSTRACT:

Background/objectives

Ocular syphilis is a vision-threatening disease that can lead to permanent blindness if left untreated. The global re-emergence of syphilis warrants greater investigations into the visual prognosis of eyes affected by this potentially devastating disease. This systematic review investigates the impact of HIV on visual acuity (VA) outcomes in ocular syphilis.

Methods

A literature search of Medline, PubMed, Embase, Clinicaltrials.gov and Cochrane Reviews was conducted for studies published between 01 January 2011 and 19 March 2022, reporting non-aggregate initial and post-treatment VA data of eyes with ocular syphilis and corresponding HIV status in patients ≥ 18 years.

Results

A total of 95 studies, including 364 patients and 568 eyes, were evalua

SUBMITTER: Wu LZ 

PROVIDER: S-EPMC10564912 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature