Acute kidney injury in hospitalized adults with chronic kidney disease: comparing cROCK, KDIGO, and combined criteria.

ABSTRACT:

Background

Acute-on-chronic kidney disease (ACKD) increases the risk of progression of chronic kidney disease (CKD). This study aimed to evaluate the ability of a novel criteria of reference change value of the serum creatinine optimized criteria for acute kidney injury in CKD (cROCK) to detect ACKD patients.

Methods

This was a retrospective observational study with a 3-year follow-up. All included patients with CKD stage 3 were evaluated using cROCK, Kidney Disease Improving Global Outcomes (KDIGO), and their combined criteria. The renal composite endpoints, major adverse cardiovascular events (MACEs), and all-cause mortality were recorded as clinical outcomes.

Results

A total of 812 patients was enrolled. The cROCK criteria detected more ACKD events than did the KDI

SUBMITTER: Sun L 

PROVIDER: S-EPMC10565458 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature