Nomogram for predicting overall survival in patients with large (>5 cm) hepatocellular carcinoma based on real-world practice.

ABSTRACT:

Background/aim

Patients with large (>5 cm) hepatocellular carcinoma (HCC) have limited treatment options, thus necessitating the identification of prognostic factors and the development of predictive tools. This study aimed to identify prognostic factors and to construct a nomogram to predict survival outcomes in patients with large HCC.

Methods

A cohort of 438 patients, who were diagnosed with large HCC at a tertiary hospital between 2015 and 2018, was analyzed. Cox proportional hazards models were used to identify key prognosticators of overall survival (OS), and an independent set of prognostic factors was used to develop a nomogram. The discrimination and calibration abilities of the nomogram were assessed and internal validation was performed using cross-validation and

SUBMITTER: Kim N 

PROVIDER: S-EPMC10565549 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature