Intraventricular Lavage vs External Ventricular Drainage for Intraventricular Hemorrhage: A Randomized Clinical Trial.

ABSTRACT:

Importance

Intraventricular lavage has been proposed as a minimally invasive method to evacuate intraventricular hemorrhage. There is little evidence to support its use.

Objective

To evaluate the safety and potential efficacy of intraventricular lavage treatment of intraventricular hemorrhage.

Design, setting, and participants

This single-blinded, controlled, investigator-initiated 1:1 randomized clinical trial was conducted at Aarhus University Hospital and Odense University Hospital in Denmark from January 13, 2022, to November 24, 2022. Follow-up duration was 90 days. The trial was set to include 58 patients with intraventricular hemorrhage. Prespecified interim analysis was performed for the first 20 participants. Data were analyzed from February to April 2023.

SUBMITTER: Haldrup M 

PROVIDER: S-EPMC10565600 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature