IgM antibody responses against Plasmodium antigens in neotropical primates in the Brazilian Atlantic Forest.

ABSTRACT:

Introduction

Zoonotic transmission is a challenge for the control and elimination of malaria. It has been recorded in the Atlantic Forest, outside the Amazon which is the endemic region in Brazil. However, only very few studies have assessed the antibody response, especially of IgM antibodies, in Neotropical primates (NP). Therefore, in order to contribute to a better understanding of the immune response in different hosts and facilitate the identification of potential reservoirs, in this study, naturally acquired IgM antibody responses against Plasmodium antigens were evaluated, for the first time, in NP from the Atlantic Forest.

Methods

The study was carried out using 154 NP samples from three different areas of the Atlantic Forest. IgM antibodies against peptides of the c

SUBMITTER: de Assis GMP 

PROVIDER: S-EPMC10565664 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature