SARS-CoV-2 Omicron variant infection affects blood platelets, a comparative analysis with Delta variant.

ABSTRACT:

Introduction

In November 2021, the SARS-CoV-2 Omicron variant of concern has emerged and is currently dominating the COVID-19 pandemic over the world. Omicron displays a number of mutations, particularly in the spike protein, leading to specific characteristics including a higher potential for transmission. Although Omicron has caused a significant number of deaths worldwide, it generally induces less severe clinical signs compared to earlier variants. As its impact on blood platelets remains unknown, we investigated platelet behavior in severe patients infected with Omicron in comparison to Delta.

Methods

Clinical and biological characteristics of severe COVID-19 patients infected with the Omicron (n=9) or Delta (n=11) variants were analyzed. Using complementary methods suc

SUBMITTER: Garcia C 

PROVIDER: S-EPMC10565689 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature