Resting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms.

ABSTRACT:

Background

Although there has been much neurobiological research on major depressive disorder, research on the neurological function of depressive symptoms (DS) or subclinical depression is still scarce, especially in older women with DS.

Objectives

Resting-state functional magnetic resonance imaging (rs-fMRI) was used to compare functional connectivity (FC) between the cerebellum and cerebral in older women with DS and normal controls (NC), to explore unique changes in cerebellar FC in older women with DS.

Methods

In all, 16 older women with DS and 17 NC were recruited. All subjects completed rs-fMRI. The 26 sub-regions of the cerebellum divided by the AAL3 map were used as regions of interest (ROI) to analyze the difference in FC strength of cerebellar seeds from ot

SUBMITTER: Feng L 

PROVIDER: S-EPMC10566116 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature