Association between the oxidative stress gene polymorphism and chronic obstructive pulmonary disease risk: a meta-analysis.

ABSTRACT:

Background

The association between the oxidative stress gene polymorphism and chronic obstructive pulmonary disease (COPD) risk has been extensively studied but the results have been controversial. This study aimed to investigate the overall association between the oxidative stress gene including glutathione S-transferase (GST), epoxide hydrolase exon (EPHX), superoxide dismutase (SOD), catalase (CAT), cytochrome P450 system (CYP) and heme oxygenase (HO-1) polymorphism and the risk of COPD.

Methods

We searched the PubMed and EMBASE database to identify studies that investigated the association between the oxidative stress gene polymorphism and risk of COPD. The relevant data were extracted and statistical analyses were performed using the Revman 5.4 and STATA 12 software. Do

SUBMITTER: Zhou T 

PROVIDER: S-EPMC10566167 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature