Insights into the liver-eyes connections, from epidemiological, mechanical studies to clinical translation.

ABSTRACT: Maintenance of internal homeostasis is a sophisticated process, during which almost all organs get involved. Liver plays a central role in metabolism and involves in endocrine, immunity, detoxification and storage, and therefore it communicates with distant organs through such mechanisms to regulate pathophysiological processes. Dysfunctional liver is often accompanied by pathological phenotypes of distant organs, including the eyes. Many reviews have focused on crosstalk between the liver and gut, the liver and brain, the liver and heart, the liver and kidney, but with no attention paid to the liver and eyes. In this review, we summarized intimate connections between the liver and the eyes from three aspects. Epidemiologically, we suggest liver-related, potential, protective and risk fact

SUBMITTER: Wu J 

PROVIDER: S-EPMC10566185 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature