Different methods for resolving overlapping UV spectra of combination medicinal dose forms of ciprofloxacin and metronidazole.
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ABSTRACT:
SUBMITTER: Sebaiy MM
PROVIDER: S-EPMC10566196 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
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Different methods for resolving overlapping UV spectra of combination medicinal dose forms of ciprofloxacin and metronidazole.
Sebaiy Mahmoud M MM El-Adl Sobhy M SM Nafea Alaa A Aljazzar Samar O SO Elkaeed Eslam B EB Mattar Amr A AA Elbaramawi Samar S SS
BMC chemistry 20231010 1
Four simple, specific, easy, precise and accurate spectrophotometric methods were developed for the first time to examine ciprofloxacin and metronidazole in combination, without having been separated beforehand by the developed methods. Ciprofloxacin and metronidazole were determined by utilizing advanced absorbance subtraction (AAS), spectrum subtraction, bivariate and ratio difference methods. Precision, repeatability, robustness, and accuracy were all determined to be within acceptable levels ...[more]
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