Cardiovascular Burden of Narcolepsy Disease (CV-BOND): a real-world evidence study.

ABSTRACT:

Study objectives

Narcolepsy is associated with cardiovascular risk factors; however, the risk of new-onset cardiovascular events in this population is unknown. This real-world study evaluated the excess risk of new-onset cardiovascular events in U.S. adults with narcolepsy.

Methods

A retrospective cohort study using IBM MarketScan administrative claims data (2014-2019) was conducted. A narcolepsy cohort, comprising adults (≥18 years) with at least two outpatient claims containing a narcolepsy diagnosis, of which at least one was non-diagnostic, was matched to a non-narcolepsy control cohort (1:3) based on cohort entry date, age, sex, geographic region, and insurance type. The relative risk of new-onset cardiovascular events was estimated using a multivariable Cox proportiona

SUBMITTER: Ben-Joseph RH 

PROVIDER: S-EPMC10566243 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature