Volatile anesthetic and outcome in acute trauma care: planned secondary analysis of the PROPPR study.

ABSTRACT:

Background

This retrospective analysis of prospectively collected data from the PROPPR study describes volatile anesthetic use in severely injured trauma patients undergoing anesthesia.

Methods

After exclusions, 402 subjects were reviewed of the original 680, and 292 had complete data available for analysis. Anesthesia was not protocolized, so analysis was of contemporary practice.

Results

The small group who received no volatile anesthetic (n = 25) had greater injury burden (Glasgow Coma Scale P = 0.05, Injury Severity Score P = 0.001, Revised Trauma Score P = 0.03), higher 6- and 24-hour mortality (P < 0.001), and higher incidence of systemic inflammatory response syndrome (P = 0.003) and ventilator-associated pneumonia (P =

SUBMITTER: Livingston CE 

PROVIDER: S-EPMC10566423 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature