GDF-15 at admission predicts cardiovascular death, heart failure, and bleeding outcomes in patients with CAD.

ABSTRACT:

Aims

We aimed to investigate the independent associations between growth differentiation factor 15 (GDF-15) level at admission and cardiovascular (CV) death, thrombotic events, heart failure (HF), and bleeding outcomes in patients with coronary artery disease (CAD).

Methods and results

We measured the plasma concentrations of GDF-15 centrally in patients from the BIomarker-based Prognostic Assessment for patients with Stable angina and acute coronary Syndrome (BIPass) registry, which consecutively enrolled patients with CAD from November 2017 to September 2019 at five tertiary hospitals in China. The outcomes included CV death, thrombotic events [myocardial infarction (MI) and ischaemic stroke], HF events [acute HF during hospitalization and hospitalization for HF post-disch

SUBMITTER: Wang J 

PROVIDER: S-EPMC10567639 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature