Pharmaco-disparities in heart failure: a survey of the affordability of guideline recommended therapy in 10 countries.

ABSTRACT:

Aims

Heart failure with reduced ejection fraction (HFrEF) is treatable but guideline-directed medical therapy (GDMT) may not be affordable or accessible to people living with the disease.

Methods and results

In this cross-sectional survey, we investigated the price, affordability, and accessibility of four pivotal classes of HFrEF GDMT: angiotensin-converting enzyme inhibitors (ACEi), angiotensin receptor blockers (ARB) or angiotensin-neprilysin inhibitors (ARNI); beta-blockers; mineralocorticoid receptor antagonists (MRA); and sodium glucose co-transporter 2 inhibitors (SGLT2i). We sampled online or community pharmacies in 10 countries across a range of World Bank income groups, assessing mean 30 day retail prescription prices, affordability relative to gross national incom

SUBMITTER: Averbuch T 

PROVIDER: S-EPMC10567666 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature