Effect of temporary freezing on postmortem protein degradation patterns.

ABSTRACT:

Background

A precise determination of time since death plays a major role in forensic routine. Currently available techniques for estimating the postmortem interval (PMI) are restricted to specific time periods or cannot be applied for individual case-specific reasons. During recent years, it has been repeatedly demonstrated that Western blot analysis of postmortem muscle protein degradation can substantially contribute to overcome these limitations in cases with different background. Enabling to delimit time points at which certain marker proteins undergo distinct degradation events, the method has become a reasonable new tool for PMI delimitation under various forensic scenarios. However, additional research is yet required to improve our understanding of protein decomposition an

SUBMITTER: Geissenberger J 

PROVIDER: S-EPMC10567868 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature