Accelerated -Rule-Out of acute Myocardial Infarction using prehospital copeptin and in-hospital troponin: The AROMI study.

ABSTRACT:

Aims

The present acute myocardial infarction (AMI) rule-out strategies are challenged by the late temporal release of cardiac troponin. Copeptin is a non-specific biomarker of endogenous stress and rises early in AMI, covering the early period where troponin is still normal. An accelerated dual-marker rule-out strategy combining prehospital copeptin and in-hospital high-sensitivity troponin T could reduce length of hospital stay and thus the burden on the health care systems worldwide. The AROMI trial aimed to evaluate if the accelerated dual-marker rule-out strategy could safely reduce length of stay in patients discharged after early rule-out of AMI.

Methods and results

Patients with suspected AMI transported to hospital by ambulance were randomized 1:1 to either accelerat

SUBMITTER: Pedersen CK 

PROVIDER: S-EPMC10568000 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature