Severe Oral Mucositis After Intensity-Modulated Radiation Therapy for Head and Neck Cancer.

ABSTRACT:

Importance

Oral mucositis (OM) is a common and debilitating adverse effect observed in patients with head and neck cancer (HNC) receiving radiation therapy (RT). Previous studies examining associations between OM and clinical outcomes were performed in the era of 3-dimensional conformal RT planning with low rates of concurrent chemotherapy, and thus may not reflect current practice.

Objective

To prospectively assess patient-reported OM and identify its associations with clinical outcomes and quality of life.

Design, setting, and participants

This cohort study performed at a single institution included 702 consecutive patients who underwent definitive or adjuvant intensity-modulated RT (IMRT) for primary HNC from February 9, 2015, to May 27, 2022. Data were analyzed fr

SUBMITTER: Iovoli AJ 

PROVIDER: S-EPMC10568356 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature