Plasma Biomarkers and Incident CKD Among Individuals Without Diabetes.

ABSTRACT:

Rationale & objective

Biomarkers of kidney disease progression have been identified in individuals with diabetes and underlying chronic kidney disease (CKD). Whether or not these markers are associated with the development of CKD in a general population without diabetes or CKD is not well established.

Study design

Prospective observational cohort.

Setting & participants

In the Atherosclerosis Risk in Communities) study, 948 participants were studied.

Exposures

The baseline plasma biomarkers of kidney injury molecule-1 (KIM-1), monocyte chemoattractant protein-1 (MCP-1), soluble urokinase plasminogen activator receptor (suPAR), tumor necrosis factor receptor 1 (TNFR-1), tumor necrosis factor receptor 2 (TNFR-2), and human cartilage glycoprotein-39 (YKL-40) measu

SUBMITTER: Le D 

PROVIDER: S-EPMC10568645 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature