A new Plasmodium vivax reference genome for South American isolates.

ABSTRACT:

Background

Plasmodium vivax is the second most important cause of human malaria worldwide, and accounts for the majority of malaria cases in South America. A high-quality reference genome exists for Papua Indonesia (PvP01) and Thailand (PvW1), but is lacking for South America. A reference genome specifically for South America would be beneficial though, as P. vivax is a genetically diverse parasite with geographical clustering.

Results

This study presents a new high-quality assembly of a South American P. vivax isolate, referred to as PvPAM (P. vivax Peruvian AMazon). The genome was obtained from a low input patient sample from the Peruvian Amazon and sequenced using PacBio technology, resulting in a highly complete assembly with 6497 functional genes. Telomeric ends were pr

SUBMITTER: De Meulenaere K 

PROVIDER: S-EPMC10568799 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature