Antifouling Zwitterionic Nanofibrous Wound Dressing for Long-Lasting Antibacterial Photodynamic Therapy.

ABSTRACT: Nanofibrous mats as a wound dressing have received great attention in recent year. The development of biocompatible dressings with antibiofouling capability and long-lasting antibacterial properties is important but challenging. Antibacterial photodynamic therapy (aPDT) effectively eliminates pathogens via a photodynamic process that can circumvent the emergence of antibiotic-resistant pathogens. In this study, we integrated the zwitterionic materials (2-methacryloyloxyethyl phosphorylcholine (MPC) moiety) and aPDT photosensitizer, methylene blue (MB), to fabricate a long-lasting antibacterial nanofibrous mat using electrospinning technology. The prepared nanofibers possessed an appropriate water absorption and retention ability, superior cytocompatibility, and antibiofouling ability again

SUBMITTER: Chang WY 

PROVIDER: S-EPMC10569006 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature