Authenticating the geographic origins of Atractylodes lancea rhizome chemotypes in China through metabolite marker identification.

ABSTRACT:

Introduction

Atractylodes lancea is widely distributed in East Asia, ranging from Amur to south-central China. The rhizome of A. lancea is commonly used in traditional Chinese medicine, however, the quality of products varies across different regions with different geochemical characteristics.

Method

This study aimed to identify the chemotypes of A. lancea from different areas and screen for chemical markers by quantifying volatile organic compounds (VOCs) using a targeted metabolomics approach based on GC-MS/MS.

Results

The A. lancea distributed in Hubei, Anhui, Shaanxi, and a region west of Henan province was classified as the Hubei Chemotype (HBA). HBA is characterized by high content of β-eudesmol and hinesol with lower levels of atract

SUBMITTER: Zhang C 

PROVIDER: S-EPMC10569125 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature