Detection of point mutations in rpoB gene of rifampin-resistant Rickettsia typhi.

ABSTRACT: The rpoB gene of rifampin-resistant Rickettsia typhi (Rif mutant) and wild-type R. typhi were sequenced and compared. The Rif mutant rpoB had three nucleotide substitutions, which resulted in amino acid changes at residues 151, 201, and 271 and may be the basis for the rifampin resistance.

SUBMITTER: Troyer JM 

PROVIDER: S-EPMC105694 | biostudies-literature | 1998 Jul

REPOSITORIES: biostudies-literature