Immunotherapy and biomarkers in patients with lung cancer with tuberculosis: Recent advances and future Directions.

ABSTRACT: Lung cancer (LC) and tuberculosis (TB) are two major global public health problems, and the incidence of LC-TB is currently on the rise. Therefore effective clinical interventions are crucial for LC-TB. The aim of this review is to provide up-to-date information on the immunological profile and therapeutic biomarkers in patients with LC-TB. We discuss the immune mechanisms involved, including the immune checkpoints that play an important role in the treatment of patients with LC-TB. In addition, we explore the susceptibility of patients with LC to TB and summarise the latest research on LC-TB. Finally, we discuss future prospects in this field, including the identification of potential targets for immune intervention. In conclusion, this review provides important insights into the complex

SUBMITTER: Yang L 

PROVIDER: S-EPMC10570004 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature