The hologenome of Daphnia magna reveals possible DNA methylation and microbiome-mediated evolution of the host genome.

ABSTRACT: Properties that make organisms ideal laboratory models in developmental and medical research are often the ones that also make them less representative of wild relatives. The waterflea Daphnia magna is an exception, by both sharing many properties with established laboratory models and being a keystone species, a sentinel species for assessing water quality, an indicator of environmental change and an established ecotoxicology model. Yet, Daphnia's full potential has not been fully exploited because of the challenges associated with assembling and annotating its gene-rich genome. Here, we present the first hologenome of Daphnia magna, consisting of a chromosomal-level assembly of the D. magna genome and the draft assembly of its metagenome. By sequencing and mapping transcriptomes from exp

SUBMITTER: Chaturvedi A 

PROVIDER: S-EPMC10570034 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature