Development and applicability of modified weight loss grading system in cancer: a real-world cohort study.

ABSTRACT:

Background

The original weight loss grading system (WLGS) was developed in western population, which did not perform effectively in cancer patients from China. This study aimed to develop and validate the modified WLGS (mWLGS) in the prognostic assessment of cancer patients in China.

Methods

A prospective multicentre real-world cohort study involving 16 842 patients diagnosed with cancer was conducted. Cox regression was used to calculate the hazard ratios for overall survival. Logistic linear regression was used to assess the odds ratio for 90-day outcomes.

Results

We calculated survival risks for the 25 mWLGS groups and clustered the approximate survival risks. Finally, we revised the prognostic grading system for mWLGS to include five grades of 0-4. Compared with t

SUBMITTER: Xie H 

PROVIDER: S-EPMC10570064 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature