Prognostic impact of cachexia by multi-assessment in older adults with heart failure: FRAGILE-HF cohort study.

ABSTRACT:

Background

Cachexia substantially impacts the prognosis of patients with heart failure (HF); however, there is no standard method for cachexia diagnosis. This study aimed to investigate the association of Evans's criteria, consisting of multiple assessments, with the prognosis of HF in older adults.

Methods

This study is a secondary analysis of the data from the FRAGILE-HF study, a prospective multicentre cohort study that enrolled consecutive hospitalized patients aged ≥65 years with HF. Patients were divided into two groups: the cachexia and non-cachexia groups. Cachexia was defined according to Evans's criteria by assessing weight loss, muscle weakness, fatigue, anorexia, a decreased fat-free mass index and an abnormal biochemical profile. The primary outcome was all-caus

SUBMITTER: Maekawa E 

PROVIDER: S-EPMC10570094 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature