Lesion location and serum levels of homocysteine are associated with early-onset post-stroke depression in acute ischemic stroke.

ABSTRACT:

Introduction

It is well known that post-stroke depression (PSD) is a psychiatric complication after stroke which leads to worse functional outcome and poorer quality of life. Some risk factors including gender, stroke severity, lesion location, homocysteine (HCY), and so on are associated with PSD. This study aims to further explore the possible relationship between serum levels of HCY and early-onset PSD and the predictive value of HCY combined with stroke characteristics for early-onset PSD.

Methods

Two hundred forty-five patients with acute ischemic stroke who met the criteria were included in this study from March 2015 to March 2017. PSD was diagnosed at 2 weeks after stroke. The severity of depressive symptoms was evaluated with the Hamilton depression scale 17 items (H

SUBMITTER: Zhou H 

PROVIDER: S-EPMC10570478 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature