StAP1 phage: an effective tool for treating methicillin-resistant Staphylococcus aureus infections.

ABSTRACT:

Introduction

Staphylococcus aureus infection has long been a serious concern in the medical field, with methicillin-resistant Staphylococcus aureus (MRSA) posing a considerable challenge to public health. Given the escalating bacterial resistance and the favorable biosafety and environmental properties of phages, the resurgence of phage therapy offers a promising alternative to antibiotics.

Methods

In this study, we isolated and characterized a MRSA phage named StAP1 from a Chinese hospital. Phenotypic and molecular analyses revealed its broad-spectrum characteristics, genomic background, and potential application in MRSA infection treatment.

Results

Morphological examination classified the phage as a member of the Herelleviridae phage family, dis

SUBMITTER: Lu Y 

PROVIDER: S-EPMC10570516 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature