Identification of staphyloxanthin and derivates in yellow-pigmented Staphylococcus capitis subsp. capitis.

ABSTRACT:

Introduction

Staphylococcus capitis naturally colonizes the human skin but as an opportunistic pathogen, it can also cause biofilm-associated infections and bloodstream infections in newborns. Previously, we found that two strains from the subspecies S. capitis subsp. capitis produce yellow carotenoids despite the initial species description, reporting this subspecies as non-pigmented. In Staphylococcus aureus, the golden pigment staphyloxanthin is an important virulence factor, protecting cells against reactive oxygen species and modulating membrane fluidity.

Methods

In this study, we used two pigmented (DSM 111179 and DSM 113836) and two non-pigmented S. capitis subsp. capitis strains (DSM 20326^T and DSM 31028) to identi

SUBMITTER: Siems K 

PROVIDER: S-EPMC10570620 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature