Pre-COVID brain network topology prospectively predicts social anxiety alterations during the COVID-19 pandemic.

ABSTRACT:

Background

Social anxiety (SA) is a negative emotional response that can lead to mental health issues, which some have experienced during the coronavirus disease 2019 (COVID-19) pandemic. Little attention has been given to the neurobiological mechanisms underlying inter-individual differences in SA alterations related to COVID-19. This study aims to identify neurofunctional markers of COVID-specific SA development.

Methods

110 healthy participants underwent resting-state magnetic resonance imaging and behavioral tests before the pandemic (T1, October 2019 to January 2020) and completed follow-up behavioral measurements during the pandemic (T2, February to May 2020). We constructed individual functional networks and used graph theoretical analysis to estimate their global and

SUBMITTER: Li Q 

PROVIDER: S-EPMC10570707 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature