Cost-Effectiveness of Antiobesity Drugs for Adolescents With Severe Obesity.

ABSTRACT:

Importance

Although the American Academy of Pediatrics has recommended treatment with antiobesity drugs for adolescents, the cost-effectiveness of antiobesity drugs for this population is still unknown.

Objective

To quantify cost-effectiveness of different antiobesity drugs available for pediatric use.

Design, setting, and participants

This economic evaluation used a Markov microsimulation model with health states defined by obesity levels. Effectiveness was measured by quality-adjusted life-years (QALYs) and costs were calculated from third-party payer perspective, estimated in 2023 US dollars over a 10-year horizon. Data were obtained from the published literature.

Intervention

Antiobesity drugs orlistat, liraglutide, semaglutide, and phentermine-topiramate v

SUBMITTER: Mital S 

PROVIDER: S-EPMC10570871 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature