Oncologic Outcome in Advanced Oral Squamous Cell Carcinoma After Refusal of Recommended Adjuvant Therapy.

ABSTRACT:

Importance

Clinicians may be confronted with patients refusing recommended adjuvant therapy (AT) after the primary resection of an advanced oral squamous cell carcinoma (OSCC). However, for this tumor entity, data are lacking regarding the oncological outcomes and associated factors after refusal of AT.

Objective

To evaluate the difference in survival and disease recurrence for patients with and without recommended AT after resection of advanced OSCC.

Design, setting, and participants

In this single-center retrospective matched cohort study, patients with advanced OSCC who refused recommended AT between January 2010 and December 2021 were matched 1:1 according to Union for International Cancer Control tumor staging with patients who completed AT.

Exposures

Pati

SUBMITTER: Mrosk F 

PROVIDER: S-EPMC10570914 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature