Risk of Carcinoma in Pleomorphic Adenomas of the Parotid.

ABSTRACT:

Importance

Surgery is the mainstay of treatment for pleomorphic adenomas (PAs) of the parotid to prevent further growth and potential future malignant transformation. While historical case series have reported transformation rates as high as 10%, there is a lack of contemporary methodologically sound data.

Objective

To examine the rate of carcinoma ex pleomorphic adenoma (CXPA) detection in untreated PAs and investigate factors associated with malignant neoplasm.

Design, setting, and participants

This cohort study reviewed all cases of primary PAs managed at a quaternary referral center between December 1990 and January 2015. Patients whose clinical presentation was compatible with a primary benign PA and whose history indicated tumor duration of over 1 year were incl

SUBMITTER: Levyn H 

PROVIDER: S-EPMC10570915 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature