Risk factors associated with monozygotic twinning in offspring conceived by assisted reproductive technology.

ABSTRACT:

Study question

What are the factors influencing the occurrence of monozygotic (MZ) twins in offspring conceived by assisted reproductive technology (ART)?

Summary answer

Parental ages, the transfer of fresh versus frozen embryos, and the grade of blastocysts are all related to MZ twinning in ART offspring.

What is known already

Offspring conceived by ART have significantly increased risk of MZ twins, which may be due to the characteristics of the infertile population. The objective of this study was to explore the incidence of monozygotic (MZ) twins after ART and to clarify the risk factors for MZ twinning.

Study design size duration

A total of 255 monozygotic twins were enrolled in this cohort study, and then matched with singletons at a ratio of 1:4 randomly

SUBMITTER: Chen N 

PROVIDER: S-EPMC10570986 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature