Hemolysis and cardiopulmonary bypass: meta-analysis and systematic review of contributing factors.

ABSTRACT:

Background

The use of cardiopulmonary bypass (CPB) is almost inevitable in cardiac surgery. However, it can cause complications, including hemolysis. Until now, there have not been any standards for reducing hemolysis from CPB. Therefore, this systematic review was conducted to determine the factors that increase or reduce hemolysis in the use of CPB.

Methods

Keywords Earches (cardiac surgery AND cardiopulmonary bypass AND hemolysis) were done on PubMed databases and Cochrane CENTRAL from 1990-2021 for published randomized controlled trials (RCTs) that studied interventions on CPB, in cardiac surgery patients, and measured hemolysis as one of the outcomes. Studies involving patients with preoperative hematological disorders, prosthetic valves, preoperative use of intra-aorti

SUBMITTER: Bhirowo YP 

PROVIDER: S-EPMC10571250 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature