Comprehensive Clinical Characterization of Decade-Long Survivors of Metastatic Breast Cancer.

ABSTRACT:

Background

Elucidating the clinical features of metastatic breast cancer (MBC) patients with an exceptionally favorable prognosis may offer insights to improve the survival of more typical patients.

Methods

We collected comprehensive real-world data on clinicopathologic characteristics, treatments, and outcomes of 110 consecutive MBC patients who survived for over ten years from the clinical data warehouse of Samsung Medical Center.

Results

The cohort included 54 hormone receptor (HR)-positive/HER2-negative (HR+/HER2-), 21 HR+/HER2+, 16 HR-/HER2+, and 14 triple-negative breast cancer (TNBC) patients. The median age at MBC diagnosis was 48.5 years. Approximately 70% of patients initially had a single-organ metastasis. The most common site of metastasis was the lung (46

SUBMITTER: Shin J 

PROVIDER: S-EPMC10571750 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature